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A random library is an indispensable tool for sequence optimization. It has the ability to generate alternative peptides that could have the potential for enhanced activity. Selected residues are randomly and simultaneously substituted with all of the other 20 natural amino acids via a shotgun approach. Our random library fabricates as many sequence variations as possible within the selected amino acid residues, allowing for the design and identification of novel and highly-active peptide sequences.
Please send your protein or peptide sequence in one-letter below with the position (s) of the amino acid to be substituted, counting from the N-Terminus. A total of 20 sequences will be generated for each positional replacement.