Description

Studies on NMA (N-methylamino acid) containing peptides reveal that NMA residues increase proteolytic stability, increase membrane permeability (lipophilicity), and alter the conformational characteristics or properties of the amide bonds. A review by Fairlie discusses many aspects of the biological activity of peptides including numerous examples of N-methylation in natural products and therapeutic agents. The effects of NMA mentioned above are important in actual and potential therapeutic compounds and the assay of biological activity of modified peptides.

Short Name CAS # Molecular Formula Molecular Weight
N-Me-Val-OH 2480-23-1 C6H13NO2 131.18
N-Me-Tyr-OH 537-49-5 C10H13NO3 195.22
N-Me-Trp-OH 526-31-8 C12H14N2O2 218.26
N-Me-Thr-OH 2812-28-4 C5H11NO3 133.15
N-Me-Ser-OH 2480-26-4 C4H9NO3 119.12
N-Me-Pro-OH 475-11-6 C6H11NO2 129.2
N-Me-Phe-OH 2566-30-5 C10H13NO2 179.22
N-Me-Orn-OH•HCl 37148-99-5 C6H14N2O2 182.65
N-Me-Nva-OH 19653-78-2 C6H13NO2 131.18
N-Me-Nle-OH 17343-27-0 C7H15NO2 145.2
N-Me-Met-OH 42537-72-4 C6H13NO2S 163.2
N-Me-Lys-OH 7431-89-2 C7H16N2O2 160.22
N-Me-Leu-OH 3060-46-6 C7H15NO2 145.2
N-Me-Ile-OH 4125-98-8 C7H15NO2 145.2
N-Me-Hyp-OH 67463-44-9 C6H11NO3 145.16
N-Me-His-OH•HCl 17451-62-6 C7H11N3O2 205.6
N-Me-Gly-OH 107-97-1 C3H7NO2 89.1
N-Me-Glu-OH 6753-62-4 C6H11NO4 161.16
N-Me-Gln-OH 300560-56-9 C6H12N2O3 160.2
N-Me-Asp-OH 4226-18-0 C5H9NO4 147.13
N-Me-Asn-OH C5H10N2O3 146.1
N-Me-Arg-OH•HCl C7H16N4O2S 224.7
N-Me-Ala-OH 3913-67-5 C4H9NO2 103.1
N-Me-Aib-OH 2566-34-9 C5H11NO2 117.15
Fmoc-N-Me-Cys(Trt)-OH 944797-51-7 C38H33NO4S 599.7

 

Reviews

There are no reviews yet.


Only logged in customers who have purchased this product may leave a review.